4th Polish Zebrafish Meeting

Welcome to the 4th Polish Zebrafish Society Meeting!

We are delighted to announce that the 4th Polish Zebrafish Society Meeting will take place at the Poznan University of Medical Sciences on February 13-14, 2025. This conference is an excellent opportunity for researchers and enthusiasts who utilize zebrafish (Danio rerio) as a model organism in their scientific investigations.

Join us for two days of engaging presentations, discussions, and networking with experts in the field. Whether you are a seasoned researcher or new to zebrafish studies, this event will provide valuable insights and foster collaborations within the zebrafish research community.

We look forward to welcoming you to Poznan for an inspiring and informative meeting. Save the date and stay tuned for more details!

Rita Fior is a Developmental Biologist, fascinated by how cells interact with each other, to deliver instructions, to collaborate, to compete or synchronize their actions. By the end of her Post–Doc, she became interested in cancer. This change in her scientific interest started with the awareness that there are several equivalent chemotherapy options, but no available test to determine the best therapy for each individual patient.

With this goal, Fior developed and optimized the zAvatar model for personalized medicine and is now a leading expert in the field. Her work has had major coverage from the scientific community (Science Leslie 2017, Fazio & Zon, 2017) and social media (National Geographic, Independent etc…) and is now considered a milestone in the field, as highlighted in a recent Nature Rev in Cancer (Fazio et al 2020) and Nature Rev in Drug Discovery. Building on the zAvatar-test outstanding predictive value, Fior is spearheading a randomized clinical trial. The ultimate goal is to provide patients and clinicians with a valuable tool for directing treatments.

In parallel, the Lab is investigating the cellular and molecular interactions that occur between human tumor cells and zebrafish innate immunity to discover new mechanisms of innate immune evasion (Póvoa et al 2021, Nature Comm).

Her work is being recognized since her PhD with several prizes and honorable mentions such as Genetics of The Year (Genetics Society), BioMED Central Research award, Crioestaminal and BIAL Clinical Medicine and Cancer Research Institute-CRI Impact Award 2023.

Rita has also extensive experience in teaching in several Master and PhD programs and was author and co-editor of a textbook in Molecular and Cell Biology of Cancer, Springer (Fior and Zilhão, 2019).

Program

DAY I	13.02.2025
10:00 - 11:00 10:00 - 11:00	Science popularization lecture (PL): "Jak mała rybka pomaga w badaniach naukowych?" Magda Dubińska-Magiera, Marta Migocka-Patrzałek, University of Wroclaw Location: Congress and Didactic Centre, Room A Zebrafish Breeding and Welfare Section Meeting Location: Medical Biology Centre, Room 2009
11:00 - 12:00 12:00-12.30	Welcome: Vice-Rector for Science Professor Michał Nowicki, MD, PhD, Poznan University of Medical Sciences Open lecture: “Fishing for a Disease - Zebrafish in Biomedical Research” Przemko Tylżanowski, Medical University of Lublin, University of Leuven Discussion panel Location: Medical Biology Centre, Room 1010
12:00 - 13:00	Zebrafish Breeding and Welfare Section Meeting "Inside the Champalimaud Fish Platform: Zebrafish Care & Colony Management" Joana Monteiro, Champalimaud Foundation, Lisbon Portugal, (lecture on-line) Location: Medical Biology Centre, Room 2009
from 12:30-	Registration
13:00 - 14:30	General Assembly of the Polish Zebrafish Society Location: Medical Biology Centre, Room 1010
14:30 - 14:45	Opening of the Conference Przemko Tylżanowski, Chairman of Polish Zebrafish Society Location: Medical Biology Centre, Room 1010
14:45 - 15:30	Keynote Lecture - "Zebrafish Avatar-test for personalized medicine" Rita Fior, Champalimaud Center, Lisbon, Portugal Location: Medical Biology Centre, Room 1010
15:30 - 16:30	Session I – Oncology Chairman: Przemko Tylzanowski Location: Medical Biology Centre, Room 1010 1) Evaluation of the Zebrafish Xenograft Model in Veterinary Oncology. Małgorzata Chmielewska-Krzesińska, University of Warmia and Mazury in Olsztyn 2) Evaluation of the Anticancer Effects of Cisplatin and EX527 in the Treatment of Head and Neck Squamous Cell Carcinoma (HNSCC). Marzena Baran, Medical University of Lublin 3) Evaluation of tyrosine kinase inhibitor-associated cardiovascular toxicity. Emilia Seta, Jagiellonian University in Kraków
16:30 - 17:00	Coffee break
17:00 - 18:45	Session II – Immunity Chairman: Piotr Podlasz Location: Medical Biology Centre, Room 1010 1) Zebrafish as a real-time model to investigate phagocyte activity and inflammation in response to amyloid-b1-42. Magdalena Marcinkowska, Jagiellonian University in Kraków 2) Clock gene cry1 knock-out affects the survival and immune response against viral infection in zebrafish larvae model. Mikołaj Mazur, Jagiellonian University in Kraków 3) The effect of 25-hydroxycholesterol (25HC) on viral load in zebrafish larvae infected with Tilapia Lake Virus (TiLV), Spring Viraemia of Carp Virus (SVCV) and Nervous Necrosis Virus (NNV). Justyna Starzyk, Jagiellonian University in Kraków 4) Streptococcus pneumoniae is targeted by two non-canonical autophagy pathways within zebrafish macrophages. Bartosz Michno, Jagiellonian University in Kraków 5) Enzybiotics: A Cutting-Edge Solution for Tackling Pathogenic Bacteria, Combating Antimicrobial Resistance and Improving Animal Care. Małgorzata Korzeniowska, Mossakowski Medical Research Institute - Polish Academy of Sciences 6) Balancing Genetic Diversity, Cost Efficiency, and Animal Welfare in Zebrafish Facility Management. Magdalena Gral, International Institute of Molecular and Cell Biology in Warsaw
18:45 - 21:00	Poster session and “Get together party” Location: Ground floor corridor
DAY II	14.02.2025
9:00 - 10:45	Session III – Diseases Models Chairman: Anna Sarosiak Location: Medical Biology Centre, Room 1010 1) Genomics dissection into heart development and disease. Cecilia Winata, International Institute of Molecular and Cell Biology in Warsaw 2) Generation and analysis of muscle glycogen phosphorylase (Pygm) deficiency zebrafish model. Magda Migocka-Patrzałek, University of Wroclaw 3) Functional studies of hereditary human mutations leading to craniofacial malformations. Paulina Krzesińska, Medical University of Lublin 4) Vibrational spectroscopy imaging in zebrafish larvae model of obesity. Grzegorz Kalisz, Medical University of Lublin 5) Using zebrafish larvae to model type 2 diabetes: effects of subchronic glucose exposure. Jagoda Szponar, Medical University of Lublin 6) Towards an understanding of mitochondrial Ca2+ transport using the zebrafish. Iga Wasilewska, Mossakowski Medical Research Institute - Polish Academy of Sciences
10:45 - 11:15	Coffee break
11:15 - 13:00	Session IV – Neurobiology & Behavior Chairman: Magdalena Chadzińska Location: Medical Biology Centre, Room 1010 1) Innovative Approach to PTZ-Induced Seizure Analysis in Zebrafish. Małgorzata Potoczna, University of Warmia and Mazury in Olsztyn, Transpharmation Poland Ltd. 2) Zebrafish as a model to evaluate the efficacy of zirconium-based Metal-Organic Frameworks in amphetamine detoxification. Anna Boguszewska-Czubara, University of Lublin 3) Study of the involvement of selected bioactive substances from Withania somnifera in the modulation of behavioral responses and gene expression for specific subunits of the GABAA receptor in danio rerio larvae under the influence of ethanol. Weronika Jarczak, Poznan University of Medical Sciences 4) Short-term exposure to nanoplastic affects nervous system-associated gene expression in the Zebrafish (Danio rerio) brain: a pilot study. Wojciech Langwiński, Poznan University of Medical Sciences 5) Assessment of indoximod toxicity in a zebrafish model. Beata Sieklucka, Medical University of Bialystok
13:00 - 13:15	Conclusions, award ceremony and closing remarks Location: Medical Biology Centre, Room 1010

REGISTRATION FEES
Regular PTZ Member	200PLN
Regular Non-Member	250PLN
PhD Student PTZ Member	150 PLN
PhD Student Non-Member	200PLN
Undergrad PTZ Member	100PLN
Undergrad Non-Member	150PLN
Technician PTZ Member	150PLN
Technician Non-Member	200PLN

REGISTRATION FEES

Regular PTZ Member

200PLN

Regular Non-Member

250PLN

PhD Student PTZ Member

150 PLN

PhD Student Non-Member

200PLN

Undergrad PTZ Member

100PLN

Undergrad Non-Member

150PLN

Technician PTZ Member

150PLN

Technician Non-Member

200PLN

Payments must be made to the account:

Citibank Handlowy

49 1030 1247 0000 0000 4771 8708

SWIFT/BIC: CITIPLPX

Poznan University of Medical Sciences

Fredry 10 Street, Poznan

with the note: the name and surname of the participant, Zebrafish2025

Withdrawal from participation:

The conference fee will not be refunded if you cancel later than one month before the start of the conference. All resignations should be submitted by e-mail to: konferencje@ump.edu.pl

Invoices:

1. The organizer issues invoices based on the payment made to the data provided in the form during registration or by e-mail to the following address: konferencje@ump.edu.pl.

2. It is possible to issue an invoice no later than the 15th day of the month following the month of sale.

3. After this date, it will be impossible to issue an invoice.

Legal basis: Deadlines for issuing invoices - general rule. Pursuant to Art. 106i section 1 of the VAT Act, the invoice must be issued no later than the 15th day of the month following the month in which the goods were delivered or the service was performed.

4. Please submit invoices with deferred payment date to: konferencje@ump.edu.pl.

Conference venue

All scientific activities of the 4th Polish Zebrafish Society Meeting as well as coffee breaks
and lunches will take place in the Medical Biology Center of the Poznan University of
Medical Sciences.

The venue is located at Rokietnicka Street, close to the City centre.
Medical Biology Center is a modern research and teaching facility. It features a number
of rooms of varying sizes and functionalities.
Medical Biology Center of the Poznan University of Medical Sciences
Rokitnicka 8
60-806 Poznan, Poland

Oral Presentation Guidelines

Presentation Duration:

Each oral presentation is allocated a total of 15 minutes, consisting of:

12 minutes for the presentation

3 minutes for Q&A and discussion

Time Management:

Presenters must strictly adhere to the allotted time. Session Chairs will rigorously enforce time limits. To ensure fairness and smooth session flow:

A warning signal will be given 2 minutes before the end of the presentation time.

The presentation will be stopped if it exceeds the 12-minute limit.

The Q&A session will end promptly after 3 minutes to maintain the schedule.

Presentation Tips:

Structure your talk clearly

Keep slides concise and visually engaging.

Rehearse beforehand to ensure you stay within the time limit.

Be prepared to address audience questions efficiently.

Thank you for your cooperation. We look forward to your insightful presentations!

Poster formatting

- All posters must be prepared in English.

- All posters must be displayed in PORTRAIT (vertical) format.

- Poster boards will accommodate A0 size posters: height 1189 mm (46.8 inches), width 841 mm (33.1 inches). Please ensure that your display will fit within these parameters. You may choose to go for the smaller size, having regard to the poster legibility.

- Do not include bibliography.

- Use sans-serif font, preferentially Verdana.